Lighting Effects on Older Adults’ Visual and Nonvisual Performance: A Systematic Review

Lighting plays an important role in daily life: It helps people perform daily activities independently and safely, and also benefits their health. This study assesses the research evidence of lighting’s impacts on older adults in four domains: (a) performance of activities of daily living and instrumental activities of daily living; (b) circadian rhythm; (c) fall prevention and postural stability; and (d) sleep quality. A comprehensive review of lighting studies on older adults’ visual and nonvisual performance was conducted using a modified PRISMA systematic review process. For the first domain, some older adults had difficulty in using the toilet, preparing meals, and doing laundry under lower illuminance. For the second domain, brighter and bluish lighting improved older adults’ circadian rhythm. For the third domain, low-intensity LED lighting affixed on door frames can help older adults maintain postural stability and prevent falling during nighttime movement. Finally, some studies concluded that receiving outdoor daylight during exercise was beneficial to older adults’ sleep quality. This study provides several methodological, theoretical, and collaborative suggestions for developing a more conclusive evidence base for lighting standards and strategies for older adults.     

Inference and Decision Making for 21st-Century Drug Development and Approval

ABSTRACT

The cost and time of pharmaceutical drug development continue to grow at rates that many say are unsustainable. These trends have enormous impact on what treatments get to patients, when they get them and how they are used. The statistical framework for supporting decisions in regulated clinical development of new medicines has followed a traditional path of frequentist methodology. Trials using hypothesis tests of “no treatment effect” are done routinely, and the p-value < 0.05 is often the determinant of what constitutes a “successful” trial. Many drugs fail in clinical development, adding to the cost of new medicines, and some evidence points blame at the deficiencies of the frequentist paradigm. An unknown number effective medicines may have been abandoned because trials were declared “unsuccessful” due to a p-value exceeding 0.05. Recently, the Bayesian paradigm has shown utility in the clinical drug development process for its probability-based inference. We argue for a Bayesian approach that employs data from other trials as a “prior” for Phase 3 trials so that synthesized evidence across trials can be utilized to compute probability statements that are valuable for understanding the magnitude of treatment effect. Such a Bayesian paradigm provides a promising framework for improving statistical inference and regulatory decision making.     

Unsettling research versus activism: how might critical disability studies disrupt traditional research boundaries?

Abstract

This article responds to the call for producing activist-oriented scholarship by engaging with theoretical and methodological approaches that explore the inclusion of women and girls with disabilities in Vietnam. We consider possibilities for connecting different forms of knowledge and activism by reflecting on research practices designed to foster social change. Specifically, we ask: how can critical disability studies be more reflexive about knowledge which privileges particular ways of knowing from the Global North? What alternative possibilities can exist to foster more inclusive and transformative knowledge that tackles systemic forms of oppressions in colonial and postcolonial contexts? Reflecting on an ongoing collaborative project in Vietnam, we argue that critical disability studies which engages with different forms of activism through critical reflections on our privileges can tackle exclusion by opening a new platform for debating social justice transnationally.     

新时代高校国防教育隐性课程开发探究

新时代高校国防教育，在利用好军事理论教学这一显性课程基础上，还需要开发隐性课程。从国防教育隐性课程内涵谈起，阐述了开发国防教育隐性课程的必要性和可行性，进而对高校国防教育隐性课程开发的策略提出了几点看法，认为应该从开发以校园环境建设为基础的隐性课程、开发以制度建设为载体的隐性课程、开发以培育大学精神为核心的隐性课程三方面进行。     

京津冀节能减排政策措施的差异与协同研究

在对京津冀1981年以来节能减排政策措施进行量化处理的基础上,建立针对节能减排政策措施有效性的计量模型,分析了京津冀节能减排政策措施的演变状况,并探究京津冀节能减排政策措施对其节能减排效果影响的差异性.研究结果表明:京津冀节能减排政策颁布经历了早期各年份相对零散、缺乏连续性到新世纪以来政策颁布数量显著增多、政策总体力度逐渐增大的过程,但三地政策总效力的增加主要是由于节能减排政策颁布数量增多引起的;京津冀三地在政策的制定过程中更多的是趋于实现短期目标,政策整体缺乏系统性和权威性;人事措施、行政措施、引导措施、财税措施、金融措施等不同节能减排政策措施对京津冀节能和减排的有效性具有明显的差异;三地对不同政策措施的使用方式、使用程度方面存在明显的差异,这对京津冀协同推进节能减排的治理工作提出挑战.论文还从京津冀完善单一节能减排政策措施的使用、加强市场手段的应用及京津冀区域协同治理等方面提出了相应政策建议.     

试论社会治理背景下政府与市场关系的经济法规制

政府与市场的关系问题是经济法规制的基于问题，如何正确看待政府与市场在经济生态系统内各自的功能及作用，是经济法规制的核心问题。因为这样的认识直接导致了经济立法的体系构建与内容规则。经济法规制是国家实施经济治理与尊重市场调节的基本依据，也是施行经济法治与社会治理的根本前提。所以，从社会治理的背景下来讨论经济法规制的社会经济发展的制度条件及制度生成条件，有利于真正建立和完善经济法规制的体系和内容，从而使得经济法治生态化地融入社会治理的结构体系内，达到优化社会制度以促进经济发展的目的。     

《泰王国民商法典》制定的历史背景

《泰王国民商法典》是在近代泰国法制改革的大背景下产生的，有着复杂的社会历史背景。曼谷王朝拉玛四世以前，泰国历经素可泰王朝、大城王朝和曼谷王朝的一部分，朝代更迭，历时漫长但在法制上却保持了相对稳定。1851年，曼谷王朝四世王拉玛四世（1851-1868）登基，拉开了泰国近代史的序幕。1852年1月，英国在第二次英缅战争之后，占领了缅甸，并觊觎泰国。1855年，英国派其驻香港的总督鲍林率使团到泰国与拉玛四世谈判，威逼泰国于1855年4月18日签订了《英暹条约》（史称《鲍林条约》）。这一个不平等条约彻底打开了泰国闭关自守的大门，欧洲列强以该条约为蓝本，威逼泰国签订了类似条约。泰国自此成为一个半殖民地国家，其法制也逐步西化，泰国的法制也这一时期完成了从古代法制向现代法制的转型。事实上，泰国法制现代化的过程，就是一个从理论到制度逐步西化的过程。《泰王国民商法典》就是在这样一个大的背景下产生的。     

新时期大学生思想政治教育的现状与对策

大学生的思想政治教育在时代背景、社会环境和大学生自身素质等方面都呈现出了与以往不同的特点。大学生思想政治教育亟需深刻的改革和创新。通过分析当前大学生思想政治教育的现状以及存在的问题，提出相应的对策进行研究。     

Using the Delphi Method to Classify Medical Specialties

One medical specialty classification system applicable for research and career counseling is the person‐oriented versus technique‐oriented taxonomy. Given that the model was conceptualized in the 1960s, verification based on how medical specialties are practiced and viewed today is necessary. Five specialists in medical career development and advising verified the categorization of specialties. Based on their review, 100% consensus was reached regarding grouping of specialties. This outcome validates the taxonomy of medical specialties and supports its continued use for medical career specialty advising and choice.     

信息技术背景下教育教学多维度创新体系研究

“互联网+”、3D打印技术为代表的信息化浪潮已经到来，创新创业教育的已经在全国展开，这既是高等教育教学的挑战，更是不可多得的机遇。为适应信息技术的需求，高等院校要未雨绸缪，及时应对，从创新体系构建信息技术要先行、教育教学创新体系构建要结合学科、专业特点进行、二级学院联动、对教师要求及激励等多个方面探讨信息技术背景下教育教学多维度创新体系。